Dynamic Light Scattering (DLS)
Introduction
Dynamic light scattering (DLS) technique is capable of measuring particle size with the advantages of accuracy, speed, and reproducibility. It has become a relatively routine characterization method in nanotechnology, helping to better understand and control the properties of nanoparticles. Currently, based on its non-invasive nature and wide measurement range, DLS technology has groundbreaking applications in biopharmaceutical development, immunosensing, polymer chemistry analysis, cellular metabolism analysis, and other fields.
Figure 1. Schematic diagram of DLS for food evaluation. (Rao P, et al., 2019)
Working Principle
The principle of operation of DLS is primarily based on measuring the speed of Brownian motion of particles in solution to derive the particle size. When particles move in solution, they are subject to irregular collisions with surrounding molecules, and such collisions result in constant changes in the velocity of particle motion. The particle size can be deduced by measuring the rise and fall of the velocity of particle motion.
Features
- Fast speed and high accuracy.
- Suitable for measuring particles from the nanometer to the micrometer scale.
- Accurate, reliable, and reproducible particle size analysis.
CD BioSciences, as specialized biophysicists, can provide comprehensive dynamic light scattering (DLS) services for biomedical, molecular research, and environmental monitoring.
Main Applications
By measuring the particle size and distribution of drug nanoparticles, we can optimize the drug delivery process and improve therapeutic efficacy. In addition, DLS has applications in the measurement of particle size and distribution of nanoscale markers in cell imaging and gene therapy. With DLS technology, we can detect and control the size and stability of drug nanoparticles to ensure drug efficacy and safety.
In the field of advanced materials, we offer DLS technology for the development, characterization, and production of new materials. By measuring the particle size and distribution of nanoscale materials, we optimize material properties and improve production efficiency.
Our technology platform provides specialized DLS analysis for measuring the particle size and distribution of nanoscale pollutants in the atmosphere.
What Can We Offer?
CD BioSciences is a biological company specializing in biophysical analysis services dedicated to providing dynamic light scattering (DLS) technology to clients. For more details, please feel free to contact us.
Reference
- Rao P, Yu Z, Han H, et al. (2019). Dynamic light scattering for food quality evaluation[M]//Evaluation technologies for food quality. Woodhead Publishing. 535-557.
For research use only, not
intended for any clinical use.
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