With a research team of accomplished bioscientists, physicists, computer scientists and mathematicians, CD BioSciences is dedicated to helping clients build biophysical models of large-scale neural activity using non-linear dynamical systems theory. We integrate experimental data from multiple modalities into a common framework to facilitate prediction, testing and possible refutation.
Movement, perception and cognition all derive from the collective activity of neurons in cortical circuits and large-scale systems throughout the brain. While much progress has been made on the causes of single neuron spikes, we do not yet have a clear understanding of the processes involved in supporting collective neural behavior in large-scale cortical systems. To date, there is no widely accepted mathematically relevant theory of neuronal clustering activity. Conventional analyses of cognitive and functional neuroimaging data have largely been conducted without the use of biophysical models of large-scale neural activity.
Models of population neuronal activity are essential for understanding both perception and behavior, as well as the determinants of large-scale neuroimaging data. Large-scale neuronal dynamics models are unique in explaining, predicting and integrating neuronal activity at the macroscopic scale of perceptual behavior and functional imaging data. Multiple arguments have demonstrated the increasing importance of large-scale brain activity models in understanding the neural origins of functional imaging data (e.g. oscillations and network dynamics) in health and disease.
Fig.1 Technical and conceptual framework for empirical testing of NMMs and NFMs. (Breakspear, 2017)
We build biophysical models of large-scale brain dynamics through detailed theoretical derivations of neuronal cluster dynamics. We provide modeling services including, but not limited to:
With extensive expertise in neurophysiology, statistical physics and non-linear dynamics, CD BioSciences has developed a variety of methods to help clients build biophysical models of large-scale neural activity. Our specialist technical services will accelerate your research into the ebbs and flows of collective behavior in complex systems. If you are interested in our services, please feel free to contact us.
CD BioSciences is a biotechnology company focused on biophysical services. We are proficient in both chemistry and biophysics, and have a comprehensive biophysical platform containing a wide range of advanced technologies.